Molecular Psychiatry: Nitrated meat products are associated with mania in humans and altered behavior and brain gene expression in rats

link to to a 12-page pdf file:

Received: 6 November 2017 / Revised: 31 March 2018 / Accepted: 1 May 2018


Our study indicates that exposure to nitrated meat products is increased in a cohort of individuals with mania. Furthermore, the feeding of preparations containing added nitrates to rats results in mania-like hyperactivity, alterations in hippocampal pathways implicated in human BPD, and changes to gut microbiota. While further investigations are warranted, individuals at risk for mania may consider limiting ingestion of added dietary nitrates

Now I know why I’m crazy over smoked meats