In a way, fortunately? for me, opiates give me incredible, debilitating nausea and vomiting. I never got any happy thoughts. I had a knee replacement 1999, one hip replaced 2000, and the other hip long delayed replaced 2013. I was born 1955. I had to take very strong anti nausea meds at least 30 minutes before the the opiate and I got off them as soon as I was cleared off the blood thinner and could take ibuprofen.
My experience was that the opiates didn’t block the pain. It was still there, I just didn’t care as much, and the nausea meds also made me even sleepier.
You get bones sawed off, you need pain relief. I am doing everything possible to avoid opiates. So it was never a temptation for me.
As a former cancer biologist who now supports biotechs and some kick-ass scientists trying to “cure cancer” (an unsophisticated term but I’ll go with that), this is possibly the most offensive thing I’ve read on this board @Miss_belle
My husband who has a PhD in cancer biology, a post doc doing bench basic science, and is an MD who completed a internal medicine residency and then worked at a few biotechs, including his last job before retiring managing cancer medication trials, would agree with you, Digga. It’s really hard work and “someone should have found a cure for cancer by now” is really demeaning a lot of people who could have made a lot more money turning in a different direction.
I’m looking up what I can online, but don’t feel like I know how she would feel or think about Ozempic, or a biological rather than (or in addition to?) psychological basis for appetites.
It certainly doesn’t seem like she was against profiting from the weight loss industry, but then I only know what the Internet tells me about her
For the record, I don’t struggle with weight, but I have struggled. I had pre-diabetes, and had success with Omada, which is like Zoom. I really enjoy online communities, in case you haven’t noticed,
There were >75000 covid related death in the US in 2023. Similar to the flu vaccine, if more people would get their covid vaccine annually those numbers would be significantly lower
That’s what clinical phase, including Ph4 (post approval) are for. Yes, every person is different but with the right sample size and selection you are able to quite accurately predict safety margins etc for a large patient population (obviously there is always a certain risk associated with every drug you might take which might not be completely captured by trials but that makes it even clearer to only take drugs when you are sick)